| Hygieia

The d-Nav® Way

An array of interventions currently exist to treat diabetes. Yet all but one—insulin—have limited efficacy. Studies demonstrate the long-term benefits of insulin therapy. However, their positive results have not been achieved in the broader population because insulin therapy places heavy demands on both patients and the healthcare system.

Can you imagine a patient seeing their physician every week on a regular basis? For many people who use insulin to manage their diabetes, that’s what it would take to achieve optimal A1C levels. This becomes clearer when we look at the insulin needs of an individual patient.

The chart below shows a single patient’s insulin needs over two and a half years. Each box represents the total amount of insulin per day that was needed in a given week. For example, the patient was started at 90 units of insulin per day. In the weeks that followed, that number rose from 90, to 93, to 96, all the way up to 109 daily units of insulin before the end of month 2. Rather than staying steady at 109 units, this patient’s insulin needs then began to drop—falling as low as 76 units by month 6. Over the two-and-a-half-year period, this patient needed as little as 60 insulin units per day and as much as 120 insulin units per day. Without frequent adjustments to the treatment plan, it is not possible to adequately support such a patient, who would typically be seen by their physician 3 times per year.

Source: Hygieia Medical LTD; data from a d-Nav® patient

This particular patient injects insulin four times per day at breakfast, lunch, dinner, and bedtime. Each injection contains a different amount of insulin because insulin needs are influenced by metabolism, which fluctuates throughout the day. Sometimes it may be necessary to raise one dose while maintaining or lowering another. For example, between July and November 2013, this patient’s bedtime dose has increased and then decreased several times, while the dinner dose remained steady. In patients with advanced diabetes, these kinds of fluctuations are common. They require frequent adjustments to the insulin treatment plan based on blood glucose patterns. Making these adjustments without the help of a healthcare professional can be difficult and intimidating—even for those who have received patient education.

Source: Hygieia Medical LTD; data from a d-Nav® patient

We believe we can help people effectively manage their diabetes. Hygieia has developed the d-Nav® Insulin Management Program to provide adjustments to insulin therapy as often as needed. It is designed for insulin users who are not yet achieving optimal results.

The d-Nav® device houses specialized FDA-cleared software that increases insulin doses when sugar patterns are above target and decreases insulin doses when sugar patterns are below target.

We recognize that technology is not enough for patients seeking to optimize their blood sugar levels. For this reason, the d-Nav® Program includes clinical support. Our clinicians communicate with patients in person and by phone. This one-on-one support gives d-Nav® users the knowledge and confidence to use insulin to achieve success.

Similar to a GPS, d-Nav® technology functions as a guide for insulin users. It knows the destination and the roads that lead there. If it senses that insulin doses are going off track, d-Nav® immediately alerts the patient, providing a dose recommendation so that they can resume their journey on a better path.

By empowering people with diabetes to adjust their insulin treatment, the d-Nav® Program provides a scalable and practical solution for diabetes management. We believe there is a better way to use insulin, and have created the d-Nav® Program to improve and simplify its use.


  1. Insulin therapy for type 2 diabetes – are we there yet? The d-Nav® story, Clinical Diabetes and Endocrinology volume 4, Article number: 8 (2018)..